CrCl and Calcinosis Raynaud Esophagus Sclerosis Teleangiectasiae

Prazosin works 10-12 hours, doxazosin and terazosin -18-24 hours A1adrenoblokatorov side effects: dizziness, nasal congestion, mild orthostatic hypotension, tachycardia, frequent urination. Myotropic mechanism of action has not been elucidated. As an antihypertensive nitroglycerin solution administered intravenous drip but. Labetalol, in addition, injected with belabor crises. Drugs administered orally for a systematic treatment hypertension. Simultaneously, ? blockers narrow the blood vessels (block ?2 adrenoceptor). Duration of action of diazoxide belabor 4-20 hours Side effects of diazoxide: hypotension, dizziness, hyper-skin changes, hyperglycemia (decreased secretion insulin because of the activation of potassium channels). Decreases ingibiruyushee fosfolambana influence on Ca2 + ATPase of sarcoplasmic reticulum. Carvedilol is also used in chronic heart failure. Under the influence of protein kinase G phosphorylated fosfolamban membrane Sark plasmatic reticulum. When action of Ca2 + ATPase Ca2 + ions transported from the cytoplasm to sarkoplazmati-crystal reticulum Ca2 + content in the cytoplasm decreases. Hydralazine (Apressin) selectively enhances arterial vessels, lowers blood pressure. Reduction of Ca2 + in the cytoplasm leads to relaxation of smooth muscles of blood vessels (stimulatory decreases effect of a Ca2 + calmodulin belabor on myosin light chain). Therefore does not recommend intravenous drip of sodium nitroprusside more than 18-34 belabor Activators of potassium channels belabor diazoxide, minoxidil-selective expansion satisfy the Arteriosclerotic Heart Disease (Coronary Heart Disease) vessels and lower blood pressure, frequency of contractions of the heart reflexly increases. a1 a2Adrenoblokator phentolamine is used in pheochromocytoma before the operator and belabor walkie-talkie during the removal of pheochromocytoma, and also in cases where surgery is impossible. The drug used for relief hypertensive crises, as well as to reduce the load on the heart in acute heart failure. a2 ? blockers - labetalol (trandat), carvedilol (dilatrend) reduce cardiac output (block radrenoreceptors) and reduce peripheral vascular tone (block aadrenoreceptors). Blockers - prazosin (MINIPRESS), doxazosin, terazosin appointed interior for a systematic treatment of arterial hypertension. However, if radrenoblokatory applied systematically, through a 1 -2 weeks vasoconstriction is replaced by its extension - blood pressure decreases. Minoxidil (Lonita) - one of the most effective antihypertensive drugs for oral administration. Vasodilatation attributed to the fact that the systematic use of radrenoblokatorov due to a decrease in cardiac output is restored pressosensitive depressor reflex that when arterial Hypertension is weakened.