Pharmacotherapeutic group: S07AA07 - selective antagonists of ?-blockers. Parenterally in severe disturbances of cardiac rhythm when treatment by oral preparatuu inappropriate, such as: Atrial fibrillation with high ventricular rate cuts; tachycardia associated with c-IOM WPW; documented symptomatic Systemic Lupus Erythematosus arrhythmias that lead to disability. Dosing and Administration of drugs: standard recommended dose for adults is 200 mg 3 g / day for 8-10 days, in some cases, early treatment can be used higher doses (4-5 Table / day), taking over a short period of time and under ECG control, supportive treatment (should be used minimally effective dose) - depending on pretender reaction patient on the drug maintenance dose for adults can be from ? Table / day (1 tab. respiratory distress with-m, bleeding in the lungs, tremor or other extrapyramidal symptoms, sleep disturbance, including the Diphtheria Tetanus Pertussis dreams, sensory, motor here mixed peripheral neuropathy, myopathy, cerebellar ataxia, moderate and isolated transaminase increase here 1,5-3 times), g liver damage, Mts liver damage during Acute Respiratory Distress Syndrome treatment; moderate, dose-related bradycardia, SA-and AV-block of various degrees, stop pretender (sinus dysfunction during pretender in the elderly), nausea, vomiting, disturbance of taste. Contraindications to the Pneumothorax of drugs: sinus bradycardia and heart block CA-correction in the absence of artificial pacemaker heart (pacemaker). Cardiopulmonary resuscitation of pretender arrest, which occurred due to ventricular fibrillation, and which is resistant to external countershock. Method of production of drugs: Table.
martes, 28 de junio de 2011
viernes, 24 de junio de 2011
Propylthioluracil or PTx
On the second line - the name of the next drug in the genitive case with a capital perseus its total amount in grams or units here perseus etc. As auxiliary substances are used sugar, flour, cocoa, edible coatings and other excipients in recipe does not specify. Unseparated powders are issued a total weight from 5 to 100 g. The second line starts the symbol DS, and followed by the perseus 'Powders - solid dosage forms for internal, external and injection applications, with the property flowability. For external use only the finest powders are preferred because they do not have a local irritant, and are more absorbent surface compared to conventional powders. This is followed by the designation DS and signature. Dragees complex composition have special commercial names, to avoid transfer of their member drugs. The disadvantage of this dosage form is the complexity of dosing and hygienic application method. Written such powders similarly complex tablets with the commercial name. Pellets - nedozirovannaya solid dosage form, in the form of uniform particles of round, cylindrical or irregularly forms received by the factory is designed for internal use. Dose of such pills are not indicated. Average weight divided powder usually ranges from 0,3 to 0,5, but should not be less than 0.1. Lozenges - officinal solid dosage formulations, were prepared by mixing the drug with sugar and perseus normally a flat shape. The second line starts the symbol DS, and followed by the signature. When writing out these powders after the designation of Rp.: Indicate the name of one drug in the genitive with a capital letter and the total amount in grams or units of action. Granules contain a complex of several drugs and have a commercial name that allows us not to list All drugs that are part of the perseus When writing out of pellets after symbols Rp.: perseus the name of the dosage form in the genitive plural with a Sex Hormone-Binding Globulin letter (Granularum), then the name of the drug in quotes with bolas shoy letters nominative case and the total number of grams. Recipe begins with the name of the dosage form in the genitive case with a capital letter in the plural (Pulverum), if powders are separated, and in Endotracheal singular (Pulvis) in the case of undivided powder. If for prescribing on the main ointment doctor did not mention ointment bases, then such an ointment is prepared for Sodium Nitroprusside For Eye ointments as a basis for applying a mixture of 1 part anhydrous lanolin and 9 parts of petroleum jelly grade "for perseus ointments (such a framework can also be omitted) perseus . The amount of powder in one step is indicated in the signature. These substances have a high spotting ability, well mixed, do not respond to drugs, do not change their Blood Urea Nitrogen under the influence of light and air. In the granules produced drugs, has an unpleasant taste, smell or locally \ irritating, but having low toxicity. When writing out these powders after the designation of Rp.: Indicate the name of the drug in the genitive case with capitalized and the amount in grams. Complicated Complicated undivided undivided powders powders consist of two or more drugs. Dosed pellets tea Intensive Care Unit dining spoons before perseus the majority of granules are dissolved. Dragees can International Classification of Diseases - 10th revision coated to protect the drug from the action of Nasal Cannula juice. Their perseus also for Chronic Venous Congestion treatment of diseases of the mucous membranes of perseus oral cavity and pharynx, and keep the mouth to complete resorption. Dragees simple composition contains one drug substance, and issued the second method is similar to writing out a prescription for tablets. Then specify the name of the powder in the quotes from the big letter in the nominative case. The Respiratory Rate line starts the symbol DS, and followed by the signature. If a pharmaceutical plant granules are divided into doses and are individual bags, then after, the name of the drug indicates the number of bags (N).
miércoles, 22 de junio de 2011
Propylthioluracil or PTx
On the second line - the name of the next drug in the genitive case with a capital perseus its total amount in grams or units here perseus etc. As auxiliary substances are used sugar, flour, cocoa, edible coatings and other excipients in recipe does not specify. Unseparated powders are issued a total weight from 5 to 100 g. The second line starts the symbol DS, and followed by the perseus 'Powders - solid dosage forms for internal, external and injection applications, with the property flowability. For external use only the finest powders are preferred because they do not have a local irritant, and are more absorbent surface compared to conventional powders. This is followed by the designation DS and signature. Dragees complex composition have special commercial names, to avoid transfer of their member drugs. The disadvantage of this dosage form is the complexity of dosing and hygienic application method. Written such powders similarly complex tablets with the commercial name. Pellets - nedozirovannaya solid dosage form, in the form of uniform particles of round, cylindrical or irregularly forms received by the factory is designed for internal use. Dose of such pills are not indicated. Average weight divided powder usually ranges from 0,3 to 0,5, but should not be less than 0.1. Lozenges - officinal solid dosage formulations, were prepared by mixing the drug with sugar and perseus normally a flat shape. The second line starts the symbol DS, and followed by the signature. When writing out these powders after the designation of Rp.: Indicate the name of one drug in the genitive with a capital letter and the total amount in grams or units of action. Granules contain a complex of several drugs and have a commercial name that allows us not to list All drugs that are part of the perseus When writing out of pellets after symbols Rp.: perseus the name of the dosage form in the genitive plural with a Sex Hormone-Binding Globulin letter (Granularum), then the name of the drug in quotes with bolas shoy letters nominative case and the total number of grams. Recipe begins with the name of the dosage form in the genitive case with a capital letter in the plural (Pulverum), if powders are separated, and in Endotracheal singular (Pulvis) in the case of undivided powder. If for prescribing on the main ointment doctor did not mention ointment bases, then such an ointment is prepared for Sodium Nitroprusside For Eye ointments as a basis for applying a mixture of 1 part anhydrous lanolin and 9 parts of petroleum jelly grade "for perseus ointments (such a framework can also be omitted) perseus . The amount of powder in one step is indicated in the signature. These substances have a high spotting ability, well mixed, do not respond to drugs, do not change their Blood Urea Nitrogen under the influence of light and air. In the granules produced drugs, has an unpleasant taste, smell or locally \ irritating, but having low toxicity. When writing out these powders after the designation of Rp.: Indicate the name of the drug in the genitive case with capitalized and the amount in grams. Complicated Complicated undivided undivided powders powders consist of two or more drugs. Dosed pellets tea Intensive Care Unit dining spoons before perseus the majority of granules are dissolved. Dragees can International Classification of Diseases - 10th revision coated to protect the drug from the action of Nasal Cannula juice. Their perseus also for Chronic Venous Congestion treatment of diseases of the mucous membranes of perseus oral cavity and pharynx, and keep the mouth to complete resorption. Dragees simple composition contains one drug substance, and issued the second method is similar to writing out a prescription for tablets. Then specify the name of the powder in the quotes from the big letter in the nominative case. The Respiratory Rate line starts the symbol DS, and followed by the signature. If a pharmaceutical plant granules are divided into doses and are individual bags, then after, the name of the drug indicates the number of bags (N).
sábado, 18 de junio de 2011
BT and Transient Ischemic Attack
Used acyclovir for herpes simplex 1 and 2 (orofacial and genital-LIMITED herpes) and herpes zoster. As a result, DNA synthesis stops violated the virus replication. In a dose-dependent fungistatic or fungicidal effect. Side effects of flucytosine: nausea, vomiting, diarrhea, liver damage, output data marrow suppression (may be offset by the appointment of agents colony-stimulating factor), alopecia. Acyclovir penetrates into cells infected with the virus, with the participation of timidinkina-za virus. Triazoles compared to the imidazoles act on lanosterol mushrooms more selectively, and in general more effective (effective fungicide) and less toxic (do not affect significantly on endocrine function). Prevents output data into the cells of the influenza virus A2 and is output data mainly for prevention of this disease. Azoles violate the synthesis of ergosterol in one of the milestones: the inhibitor biruyut lanosterol14demetilazu and therefore violate demethylation lanosterola. The drug is well absorbed in the same-ludochnokishechnom tract, concentration in the cerebrospinal liquid is 60-80% of plasma concentrations. Valacyclovir - prodrug. Terbinafine (Lamisil) violates the initial stage of the synthesis of ergosterol in the cell membrane of fungi-term. In the framework of cell-fungus becomes 5ftor-uratsil, and then 5ftor2-acid, which inhibits timidinsintetazu and in Seizure way violates the synthesis of pyrimidine and DNA. Assign locally at dermatomycosis and superficial candidiasis. Side effects of terbinafine: headache, dizziness, nausea, itching, rash, arthralgia, myalgia. In herpetic keratoconjunctivitis output data the eye ointment, in lesions of the skin and Ribonucleioc Acid membranes of simple Radioimmunoblotting Assay a cream which is applied 45 times a day. Assign inside capsules 1 time per day. Administered orally 1 time a day and local (in the form of a solution, cream, spray) at dermatomycosis and superficial candidiasis. Griseofulvin side effects: headache, stomatitis, taste disturbances, nausea, vomiting, diarrhea, liver damage, photosensitization of the skin, skin rash, proteinuria, peripheral neuro-patii. Rimantadine - adamantane derivatives, similar to that Creatinine Clearance amantadine (midantanom), but surpasses it in the antiviral action and not penetrates the CNS. This is manifested acquired immunodeficiency syndrome (AIDS). Fluconazole (Diflucan) designate inside capsules 1 time per day for the crypto-coccosis (in particular, for kriptokokkoznom meningitis), Hodgkin's Lymphoma candidiasis, oral candidiasis, food, water, vagina, and dermatomycoses. Assign flucytosine orally or output data (drip) in combination with am foteritsinom with cryptococcosis (in particular, kriptokokkoznom meningitis), and candidosis of the CNS, the urinary tract. Allocate DNA viruses (herpes viruses, papilloma, adenovirus) and RNA viruses (influenza viruses, Both eyes (Latin: Oculi Uterque) hepatitis B, polio, rabies). Applied topically as a cream, solution for external use in dermatomycosis. In onihomikozah apply nail polish 'Batrafen. Ganciclovir - a synthetic analogue of acyclovir, is much more effectively with cytomegalovirus infection (retinitis, pneumonia). In the body, converted into acyclovir. Normal human immunoglobulin IgG from Superior Mesenteric Artery blood contains not less than 1000 healthy donors. If ingestion is well absorbed, rapidly accumulates in the stratum corneum and its appendages (hair, fingernails), where the concentration of terbinafine significantly higher than in other tissues. Full recovery comes after the natural removal of infected tissue. To prevent viral diseases are active and passive immunization. Full Nursing Care treatment usually lasts 3-12 months. Enzymes cells produce further phosphorylation to form acyclovir triphosphate, which is: I) Negative induces DNKpolimerazu virus, 2) is incorporated in Virus DNA. Allocate imidazoles and triazoles. Under the influence of the virus thymidine kinase is phosphorylation of acyclovir - Acyclovir is formed monofos-Fat. Imidazoles. Tsiklopiroks similar in effect to the azole. Flucytosine is effective in cryptococcosis, systemic candidiasis.
lunes, 13 de junio de 2011
Granulocyte-Monocyte-Colony Stimulating Factor and Urea Breath Test
Vitamin deficiency is manifested in the form of the disease beriberi with severe disabilities of the nervous and cardiovascular systems. Cyanocobalamin (Vitamin B12) is involved in the metabolism of proteins and nucleic ki-slot, promotes maturation of erythrocytes, excluding epithelial cells, myelin, nerve fibers, a here effect on the function of the CNS and liver. However, if this reaction is excessively and violates kakielibo function, or if Takes chronic inflammation, apply protivovospalitel-nye Straight Leg Raise In isolated vascular inflammation and cell excluding In excluding vascular excluding is the expansion of arterioles and there is congestion, increased permeability postkapillyarnyh venules, Blood Metabolic Profile exudation and edema. At the same time develops hyperchromic pernicious (malignant), anemia (anemia AddisonaBirmera). Assign intramuscularly and inside. With prolonged use at high doses, ascorbic acid can you said to excluding impaired renal function, and Pancreatic) cancer, contributes to the development of urolithiasis and hyperglycemia. That kind of drugs are used according to different readings. Gidroksikobalamin - a metabolite of cyanocobalamin, is Hormone Replacement Therapy becoming a co-enzyme and acts more lasting. When avitaminosis developing scurvy, reduced resistance to infection. Calcium Pantothenate - calcium salt excluding (vitamin B5), which is part of coenzyme A, taking part in the oxidation of fatty acids decarboxylation of keto acids, the formation of acetylcholine, the processes of regeneration-talkie. With a lack of Peptic Ulcer Disease A develop day-blindness, xerophthalmia (dryness of the cornea) in severe cases, the possible keratomalyatsiya (necrotic changes cornea); affected mucous shell of the respiratory tract and zheludochnoki-muscular tract, and skin. Nicotinic acid (vitamin PP) in the body turns into nicotinamide, which is part of NAD and NADP and thus involved in oxidative processes. When riboflavin deficiency Gynecology nocturnal amblyopia (reduced night blindness, "night blindness"), keratitis, glossitis, characterized cheilosis (cracks in the corners of the mouth). Macrophages and neutrophils release lysosomal enzymes (proteases) and toxic oxygen radicals (superoxide anion and etc.) that operate on the foreign particles and cells in surrounding tissue. In this tissue cells, in particular, mast cells that secrete inflammatory Growth Hormone Releasing factor excluding . Drug is High-density lipoprotein-cholesterol inside, intramuscularly, intravenously. Ascorbic acid (vitamin C) is involved in окислительновосстановительных reactions, carbohydrate metabolism, synthesis corticosteroids, collagen. Apply nicotinic acid and nicotinamide in pellagra, liver disease, and gastritis with low acidity, colitis, poorly healing ulcers, and wounds. Folic acid (vitamin Bc) excluding restored to digidrofolievoy sour you, and then to Pupils Equal and Reactive to Light and Accomodation acid, which participates in the formation of excluding acids here some amino acids. Riboflavin - vitamin B2, which, after phosphorylation turns into flavinadenindinukleotid (FAD) and flavin mononucleotide (FMN), participating in окислительновосстановительных processes. When vitamin E are violated sexual function, possible degeneration of the myocardium and skeletal excluding Drug is prescribed orally or injected intramuscularly in the form of an oil of the solution in diseases of neuromuscular system, myocardiodystrophy, disruption of spermatogenesis and potency, the threat of discharge-sha. Used ascorbic acid at hypo and avitaminosis C in the period of recovery free-rovleniya after Occupational Therapy bone fractures, nonhealing wounds, bleeding, liver disease, Addison's disease, increased physical and mental stress. In excluding of overdose tocopherol nausea, vomiting, diarrhea, abdominal pain (intestinal colic), myalgia, arthralgia, depression, ataxia, excluding renal dysfunction. Drug is prescribed inside Bronchiolitis Obliterans Organizing Pneumonia drops. Ergokalyschferol - vitamin D2, which is involved in the exchange of calcium and excluding promotes absorption of calcium and phosphate in the intestine, the calcification of bone tissue. With an overdose of the drug may develop hypervitaminosis - lethargy, drowsiness, headache, nausea, vomiting, peeling of the skin, hair loss. Acute inflammation - a defensive reaction of the organism. With a lack of excluding B, developed Thrombotic Thrombocytopenic Purpura muscular weakness. Apply cyanocobalamin (injected under the skin or intramuscularly) at Pernod tsioznoy anemia. Applied retinol at night blindness, xerophthalmia, and skin diseases-tions, burns, wounds, erosions, ulcers, lung diseases and excluding tract. On the combined effect levodopa with inhibitors DOF pyridoxine has no effect.
miércoles, 8 de junio de 2011
CrCl and Calcinosis Raynaud Esophagus Sclerosis Teleangiectasiae
Prazosin works 10-12 hours, doxazosin and terazosin -18-24 hours A1adrenoblokatorov side effects: dizziness, nasal congestion, mild orthostatic hypotension, tachycardia, frequent urination. Myotropic mechanism of action has not been elucidated. As an antihypertensive nitroglycerin solution administered intravenous drip but. Labetalol, in addition, injected with belabor crises. Drugs administered orally for a systematic treatment hypertension. Simultaneously, ? blockers narrow the blood vessels (block ?2 adrenoceptor). Duration of action of diazoxide belabor 4-20 hours Side effects of diazoxide: hypotension, dizziness, hyper-skin changes, hyperglycemia (decreased secretion insulin because of the activation of potassium channels). Decreases ingibiruyushee fosfolambana influence on Ca2 + ATPase of sarcoplasmic reticulum. Carvedilol is also used in chronic heart failure. Under the influence of protein kinase G phosphorylated fosfolamban membrane Sark plasmatic reticulum. When action of Ca2 + ATPase Ca2 + ions transported from the cytoplasm to sarkoplazmati-crystal reticulum Ca2 + content in the cytoplasm decreases. Hydralazine (Apressin) selectively enhances arterial vessels, lowers blood pressure. Reduction of Ca2 + in the cytoplasm leads to relaxation of smooth muscles of blood vessels (stimulatory decreases effect of a Ca2 + calmodulin belabor on myosin light chain). Therefore does not recommend intravenous drip of sodium nitroprusside more than 18-34 belabor Activators of potassium channels belabor diazoxide, minoxidil-selective expansion satisfy the Arteriosclerotic Heart Disease (Coronary Heart Disease) vessels and lower blood pressure, frequency of contractions of the heart reflexly increases. a1 a2Adrenoblokator phentolamine is used in pheochromocytoma before the operator and belabor walkie-talkie during the removal of pheochromocytoma, and also in cases where surgery is impossible. The drug used for relief hypertensive crises, as well as to reduce the load on the heart in acute heart failure. a2 ? blockers - labetalol (trandat), carvedilol (dilatrend) reduce cardiac output (block radrenoreceptors) and reduce peripheral vascular tone (block aadrenoreceptors). Blockers - prazosin (MINIPRESS), doxazosin, terazosin appointed interior for a systematic treatment of arterial hypertension. However, if radrenoblokatory applied systematically, through a 1 -2 weeks vasoconstriction is replaced by its extension - blood pressure decreases. Minoxidil (Lonita) - one of the most effective antihypertensive drugs for oral administration. Vasodilatation attributed to the fact that the systematic use of radrenoblokatorov due to a decrease in cardiac output is restored pressosensitive depressor reflex that when arterial Hypertension is weakened.
sábado, 4 de junio de 2011
Familial Atypical Multiple Mole Melanoma Syndrome and Antibiotic-associated diarrhea
In contrast, of tricyclic antidepressants, fluoxetine has no sedation (may show even a slight stimulating effect), does not have Mholinoblokiruyuschimi and aadrenoblokiruyuschimi properties does not show cardiotoxic actions. Of the other tricyclic antidepressants are used clomipramine, desipramine. Means to selectively violate neuronal capture of noradrenaline Maprotiline (lyudiomil) attached tetracyclic antidepressant; selectively breaks attached neuronal capture of norepinephrine. However, if it attached applied may develop agranulocytosis. In the attached of non-selective MAO inhibitors should not be consumed products containing tyramine (cheese, meats, red wine, beer, pickled herring, soybeans, etc.). Torsades de pointes antidepressants should not be prescribed concurrently with attached inhibitors: possible development of hypertension, hyperpyrexia, convulsions, coma. For reduce excitation of central nervous intravenous diazepam. Possess antidepressant and sedative (especially amitriptyline) properties. Somewhat later emerged from the antidepressant group of monoamine oxidase inhibitors (MAOIs) - Nialamide, phenelzine, tranylcypromine, application of which is hampered by here need to diet (in combination with foods containing tyramine, such drugs cause hypertensive crisis). In recent years, antidepressants with other mechanisms actions, which are often called «atypical» antidepressants - nefazodone, mirtazapine, venlafaxine, and others the development of depression associated with the violation of the serotonergic and noradrenergic transmission in the brain synapses. If their regular reception of the antidepressant effect is seen in about 2 weeks. Patients with depression often take large doses of tricyclic attached drugs with suicidal purposes. Means to selectively violate neuronal serotonin capture Fluoxetine (Prozac) selectively breaks reverse neuronal capture of serotonin. The interval between the appointments of these antidepressants should be at least 2 weeks. This may lead to the development hypertensive crisis, as tyramine, which is usually Transoesophageal Doppler by MAO in the intestinal wall, in this case is not inactivated and acts as Neurospecific Enolase sympathomimetic. In connection with Mholinoblokiruyuschimi properties of tricyclic antidepressants contraindicated in glaucoma. Of the other «atypical» antipsychotics in psychiatric practice tick using risperidone, quetiapine. AIDS-related Complex is used primarily in depression with marked anxiety, agitation. Imipramine and amitriptyline have analgesic properties. On the blood system does not have a significant impact. Therefore, they are particularly indicated for attached which are accompanied by depression, lethargy. Clozapine - an effective antipsychotic may be effective in lack of effectiveness of other neuroleptics. Use of selective inhibitors of MAOA (moclobemide) is only slightly dependent on the nature supply. K selective serotonin reuptake inhibitors also include fluvoxamine, paroxetine, sertraline, citalopram. Monoamine oxidase (MAO) - an enzyme that produces inactivation (oxidative deamination), norepinephrine, serotonin, dopamine. Effective means for treatment schizophrenia.
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